Hepatic Encephalopathy Market Scope
According to the Center for Disease Control and Prevention (CDC), in 2017, around 4.5 million adults were diagnosed with liver disease in the United States. Moreover, the number of deaths due to chronic liver disease and cirrhosis accounted for 40,545 in 2017. Hepatic encephalopathy (HE) is a disorder that arises due to accumulated toxins in the brain which leads to liver diseases. It is a syndrome that occurs in patients with liver dysfunction and is defined as a spectrum of neuropsychiatric abnormalities, after exclusion of brain disease. Further, increasing prevalence of liver disease and high mortality rate, such factors are driving the Global Hepatic Encephalopathy market.
According to AMA, the Global Hepatic Encephalopathy market is expected to see growth rate of 6.5%
The Global Hepatic Encephalopathy market is moderately fragmented with several players. The market is exhibiting a moderate growth mostly due to an upsurge in the patient population suffering from the cirrhosis disease. Different types of therapeutic drugs in the pipeline for the treatment of HE. Several clinical trial drug treatment for HE are being carried out by researchers. For instance, KLS-13019 is a drug developed by Kanna Life Sciences and is currently under the pre-clinical phase. It is a cannabinoid, which acts on cannabinoid receptors in cells that alter the neurotransmitter release inside the brain.
ASKA Pharmaceutical Co., Ltd.(Japan), Cosmo Pharmaceuticals N.V. (Ireland), Lupin Limited (India), Kaleido Biosciences (United States), Kannalife Sciences, Inc. (United States), Bausch Health Companies Inc. (Canada), Ferring Pharmaceuticals Inc. (Switzerland), Mallinckrodt Pharmaceuticals (United Kingdom), Umecrine Cognition AB (Sweden) and Norgine B.V. (Netherlands) are some of the key players that are part of study coverage.
About Approach
The research aims to propose a patent-based approach in searching for potential technology partners as a supporting tool for enabling open innovation. The study also proposes a systematic searching process of technology partners as a
preliminary step to select the emerging and key players that are involved in implementing market estimations. While patent analysis is employed to overcome the aforementioned data- and process-related limitations, as expenses occurred in that technology allows us to estimate the market size by evolving segments as target market from total available market.
Segmentation Overview
The study have segmented the market of Global Hepatic Encephalopathy market , by Application (Acute Liver Failure, Portal Systemic Bypass Without Liver Disease and Liver Cirrhosis) and Region with country level break-up.
On the basis of geography, the market of Hepatic Encephalopathy has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico).
Market Leaders and their expansionary development strategies
In 2017, Umecrine Cognition company is developing a therapy that represents a new target class for several major central nervous system (CNS)-related disorders. The lead compound GR3027 is presently in clinical development for HE. The company plans to demonstrate Phase II data of GR3027 for the treatment of HE in 2020.
January 2018, Rebiotix Inc.(Ferring Pharmaceuticals Inc.) is developing a drug i.e. RBX2477 that can be administered orally for HE. The drug is presently under Phase I clinical trial. It is an antibiotic that reduces the production of ammonia by inhibiting the growth of ammonia-producing colonic bacteria.
Market Trend
- Rising Awareness Program on Liver Disease and Liver Cancer
- The Emergence of Novel Treatment Target for HE
Market Drivers
- Increasing Number of Products in the Pipeline for the Treatment of HE
- Growing Prevalence of Liver Diseases
- Increased Mortality Rate & Hospitalizations
Opportunities
- Rising Number of Clinical Trials on the Effective Drug Treatment for HE
Restraints
- Cost Factor Associated in Treatment of Hepatic Encephalopathy
Challenges
- Delay and Inaccurate Diagnosis for HE is Posing a Challenge for the Market
Key Target Audience
Hepatic Encephalopathy Drug Manufacturers, Pharmaceutical Companies, Government & Regulatory Bodies, Industry Associations, Marketing firms, Research Organizations and Others