Industry Background:
A multitude of innovative therapeutic antibody formats based on modification of the conventional IgG format have arisen in recent years. The increase of interest in this area reflects a pressing need for an additional repertoire of therapeutic molecules which retain the exquisite binding specificity and low intrinsic toxicity of monoclonal antibodies (mAbs), whereas engineering additional features which enhance clinical efficacy, for instance, by improving tissue perfusion or demonstrating increased specificity for a defined cell type.This growth is primarily driven by Rising Number of Collaborations for R&D in Next-Generation Antibody Therapeutics and Increasing Prevalence of Chronic Diseases.
Globally, a noticeable market trend is evident Growing Popularity of ADC Technology. Major Players, such as ImmunoGen, Inc. (United States), Bayer AG (Germany), Biogen (United States), Xencor, Inc. (United States), F. Hoffmann-La Roche Ltd. (Switzerland), Kyowa Hakko Kirin Co., Ltd. (Japan), Dyax Corp. (United States), Seattle Genetics, Inc. (United States), Pfizer (United States) and Bristol-Myers Squibb (United States) etc have either set up their manufacturing facilities or are planning to start new provision in the dominated region in the upcoming years.
Key Developments in the Market:
On 28 March, 2019 - AstraZeneca has entered into a global development and commercialization collaboration agreement with Daiichi Sankyo Company, Limited (Daiichi Sankyo) for trastuzumab deruxtecan (DS-8201), a proprietary antibody-drug conjugate (ADC) and potential new targeted medicine for cancer treatment.
Market Drivers
- Rising Number of Collaborations for R&D in Next-Generation Antibody Therapeutics
- Increasing Prevalence of Chronic Diseases
Market Trend
- Growing Popularity of ADC Technology
Restraints
- Higher Costs of Therapeutics
Opportunities
Technological Advancements in Antibody Therapeutics
Challenges
Stringent Regulatory Related to Antibody Therapeutics and Lengthy Approval Processes
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