About Antisense Therapy
Antisense remedy is an strategy to conflict ailments the use of quick DNA-like molecules known as antisense oligonucleotides. Recently, antisense remedy has emerged as an thrilling and promising approach for the cure of a range of neurodegenerative and neuromuscular disorders. Antisense remedy includes downregulation of gene expression by means of complementary oligonucleotide binding to goal mRNA. Antisense oligonucleotides are quick single-stranded DNA sequences engineered to be complementary to the particular ‘sense’ (5' to 3') orientation of mRNA coding for the focused protein.
Attributes | Details |
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Study Period | 2018-2030 |
Base Year | 2023 |
Unit | Value (USD Million) |
The market is seeing moderate market players, by seeing huge growth in this market the key leading vendors are highly focusing towards the production technologies, efficiency enhancement and product life. There is various growth opportunity in this market which is captured by leading players via tracking the ongoing process enhancement and huge invest in market growth strategies. Analyst at AMA Research estimates that United States Players will contribute the maximum growth to Global Antisense Therapy market throughout the forecasted period. Established and emerging Players should take a closer view at their existing organizations and reinvent traditional business and operating models to adapt to the future.
GlaxoSmithKline Plc (United Kingdom), Bio-Path Holdings Inc. (United States), Calando Pharmaceuticals (United States), Ionis Pharmaceuticals (United States), Enzon Pharmaceuticals Inc (United States), Gradalis (United States), Sanofi S.A (France), miRagen Therapeutics (United States), Olix Pharmaceuticals (South Korea) and OncoGeneX Pharmaceuticals (Canada) are some of the key players that are part of study coverage. Additionally, the Players which are also part of the research coverage are Regulus Therapeutics (United States), Rexahn Pharmaceuticals (United States), Rxi Pharmaceuticals (United States), Santaris Pharma A/S (Roche) (Denmark) and Others.
Segmentation Overview
AMA Research has segmented the market of Global Antisense Therapy market by and Region.
On the basis of geography, the market of Antisense Therapy has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico). If we see Market by Route of Administration, the sub-segment i.e. Pulmonary Delivery will boost the Antisense Therapy market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by End-users, the sub-segment i.e. Hospitals will boost the Antisense Therapy market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by Indication, the sub-segment i.e. Oncology will boost the Antisense Therapy market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth.
Influencing Trend:
Increase in Prevalence of Chronic Disease along with rise in Elderly Population
Market Growth Drivers:
Rise in the Prevalence Diseases such as Cancer, Cardiovascular Disorders and Others
Challenges:
Stringent Regulations, and Long Product Approval Process
Restraints:
High Cost Associated with of RNA Interference-based Drugs
Opportunities:
Rising Research activities in Gene Therapy, Immunotherapy & Cell Therapy Treatments and Rising Healthcare Expenditure
Market Leaders and their expansionary development strategies
In March 2020, Secarna Pharmaceuticals GmbH & Co. KG ("Secarna"), a biopharmaceutical company focusing on the discovery and development of next generation antisense oligonucleotide (ASO) therapies to address challenging or previously undruggable targets via its LNAplusTM platform, today announced that the Company signed a Research, Development and Transfer Agreement with Lipigon Pharmaceuticals AB ("Lipigon"). Under this agreement, Lipigon acquires certain antisense drug candidates, which were developed with Secarna's.
In 2022, Pfizer Inc. and Ionis Pharmaceuticals, Inc. announced the discontinuation of the Pfizer-led clinical development program for vupanorsen (PF-07285557), an investigational antisense therapy that was being evaluated for potential indications in cardiovascular (CV) risk reduction and severe hypertriglyceridemia (SHTG).
Key Target Audience
Venture Capitalists and Private Equity Firms, Government Bodies, Corporate Entities, Government and Private Research Organizations and Others
About Approach
To evaluate and validate the market size various sources including primary and secondary analysis is utilized. AMA Research follows regulatory standards such as NAICS/SIC/ICB/TRCB, to have a better understanding of the market. The market study is conducted on basis of more than 200 companies dealing in the market regional as well as global areas with the purpose to understand the companies positioning regarding the market value, volume, and their market share for regional as well as global.
Further to bring relevance specific to any niche market we set and apply a number of criteria like Geographic Footprints, Regional Segments of Revenue, Operational Centres, etc. The next step is to finalize a team (In-House + Data Agencies) who then starts collecting C & D level executives and profiles, Industry experts, Opinion leaders, etc., and work towards appointment generation.
The primary research is performed by taking the interviews of executives of various companies dealing in the market as well as using the survey reports, research institute, and latest research reports. Meanwhile, the analyst team keeps preparing a set of questionnaires, and after getting the appointee list; the target audience is then tapped and segregated with various mediums and channels that are feasible for making connections that including email communication, telephonic, skype, LinkedIn Group & InMail, Community Forums, Community Forums, open Survey, SurveyMonkey, etc.