About Dystrophic Epidermolysis Bullosa Treatment
Epidermolysis bullosa (EB) is a category of inherited blistering skin diseases. Although the community is clinically and genetically diverse, both EB types are linked to mechanically induced skin blistering and fragility. Some EB forms have documented causative gene mutations. EB simplex (EBS), junctional EB (JEB), dystrophic EB (DEB), and Kindler syndrome are all forms of EB (KS). The morphological stage of blister formation is used to classify blisters. However, over the last decade, a number of significant developments have been made that push the clinic closer to modern therapeutic approaches that include gene therapy, protein replacement therapy, cell therapy (allogeneic fibroblasts, Mesenchymal Stromal Cells (MSCs), bone marrow stem cell transplant, revertant mosaic keratinocyte culture/vaccination, gene editing/engineering, and the clinical application of inducible pluripotent stem cells).
Attributes | Details |
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Study Period | 2018-2028 |
Base Year | 2022 |
Unit | Value (USD Million) |
The companies are exploring the market by adopting mergers & acquisitions, expansions, investments, new service launches and collaborations as their preferred strategies. The players are exploring new geographies through expansions and acquisitions to avail a competitive advantage through combined synergies. Analyst at AMA Research estimates that United States Players will contribute the maximum growth to Global Dystrophic Epidermolysis Bullosa Treatment market throughout the forecasted period. Established and emerging Players should take a closer view at their existing organizations and reinvent traditional business and operating models to adapt to the future.
Krystal Biotech (United States), Castle Creek Biosciences, Inc. (United States), Abeona Therapeutics, Inc. (United States), Amryt Pharma plc (United Kingdom), Wings Therapeutics (United States), Phoenix Tissue Repair (United States), InMed Pharmaceuticals, Inc. (Canada), RegeneRx (United States) and Holostem Terapie Avanzate S.r.l. (Italy) are some of the key players that are part of study coverage. Additionally, the Players which are also part of the research coverage are Pfizer Inc. (United States), Galderma International (Switzerland), Mylan N.V. (Netherland) and ConvaTec (United Kingdom).
Segmentation Overview
AMA Research has segmented the market of Global Dystrophic Epidermolysis Bullosa Treatment market by and Region.
On the basis of geography, the market of Dystrophic Epidermolysis Bullosa Treatment has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico). If we see Market by Therapy, the sub-segment i.e. Gene therapy will boost the Dystrophic Epidermolysis Bullosa Treatment market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by Treatment, the sub-segment i.e. Antibiotics will boost the Dystrophic Epidermolysis Bullosa Treatment market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by Category, the sub-segment i.e. Dominant Dystrophic Epidermolysis Bullosa (DDEB) will boost the Dystrophic Epidermolysis Bullosa Treatment market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by End Use, the sub-segment i.e. Hospitals will boost the Dystrophic Epidermolysis Bullosa Treatment market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth.
Influencing Trend:
Emergence of Advance Therapeutics and Effective Medication
Market Growth Drivers:
Prevalence of Dystrophic Epidermolysis Bullosa, Rising Geriatric Population and Increasing Healthcare Infrastructure
Challenges:
Lack of Trained Professionals
Restraints:
High-Cost Expenses
Opportunities:
Growing Demand in Emerging Regions Particularly Asia
Market Leaders and their expansionary development strategies
In October 2023, DEB patient advocacy groups form a global alliance this initiative aims to unite the DEB community, share resources, and advocate for improved research funding and access to treatment for all patients worldwide.
In September 2023, AlloVir receives Fast Track designation from FDA for ALTO-101 this cell therapy candidate uses genetically modified T cells to target and eliminate the faulty immune cells responsible for blistering in DEB, potentially offering a personalized and disease-modifying treatment.
Key Target Audience
Dystrophic Epidermolysis Bullosa Treatment Providers, New Entrants and Investors, Venture Capitalists, Government Bodies, Corporate Entities, Government and Private Research Organizations and Others
About Approach
To evaluate and validate the market size various sources including primary and secondary analysis is utilized. AMA Research follows regulatory standards such as NAICS/SIC/ICB/TRCB, to have a better understanding of the market. The market study is conducted on basis of more than 200 companies dealing in the market regional as well as global areas with the purpose to understand the companies positioning regarding the market value, volume, and their market share for regional as well as global.
Further to bring relevance specific to any niche market we set and apply a number of criteria like Geographic Footprints, Regional Segments of Revenue, Operational Centres, etc. The next step is to finalize a team (In-House + Data Agencies) who then starts collecting C & D level executives and profiles, Industry experts, Opinion leaders, etc., and work towards appointment generation.
The primary research is performed by taking the interviews of executives of various companies dealing in the market as well as using the survey reports, research institute, and latest research reports. Meanwhile, the analyst team keeps preparing a set of questionnaires, and after getting the appointee list; the target audience is then tapped and segregated with various mediums and channels that are feasible for making connections that including email communication, telephonic, skype, LinkedIn Group & InMail, Community Forums, Community Forums, open Survey, SurveyMonkey, etc.