Industry Background:
PEGylation is the method of attaching polyethylene glycol polymer chains to molecules, such as a drug, therapeutic protein, or vesicle, by covalent and non-covalent means. By changing the electrostatic binding, validation, and hydrophobicity of the molecule, PEGylation increases drug stability and solubility while lowering immunogenicity. PEGylation has been applied to a wide range of proteins, therapeutic peptides, and small drug molecules in order to enhance or change pharmacokinetic parameters and reap different benefits. The rising prevalence of chronic diseases such as cancer, kidney disease, and rheumatoid arthritis is a major factor driving market development. The creation of various therapeutics for the treatment of chronic kidney disease based on PEGylated proteins is a hot topic these days. Furthermore, biotechnology and pharmaceutical companies are increasing their investments in research and development projects, which is fueling business growth. Protein-based drugs are increasingly being preferred over non-protein-based drugs because pegylation improves protein circulation and half-life, thus enhancing efficacy.
Attributes | Details |
---|
Study Period | 2017-2027 |
Base Year | 2021 |
Unit | Value (USD Million) |
Key Companies Profiled | Merck KGaA (Germany), Thermo Fisher Scientific (United States), Celares GmbH (Germany), Astrazeneca plc (United Kingdom), Pfizer Inc. (United States), Biogen inc (United States), F. Hoffmann-La Roche Ltd (Switzerland), Horizon Pharma plc (Ireland), Shire plc (United States) and Quiapeg Pharmaceuticals Holding Ab (Sweden) |
CAGR | 9.8% |
According to AMA, the market for Pegylated Proteins is expected to register a CAGR of 9.8% during the forecast period to 2027. This growth is primarily driven by High Prevalence of Chronic Diseases and Advantages offered by PEGylation.
Globally, a noticeable market trend is evident Growth in Adoption of PEGylated Protein Therapeutics. The Telecom Services sector in the North America region has been increasing at a sustainable rate and further growth is expected to be witnessed over the forecast period, owing to the robust investments and expansion in production facilities in the region. Major Players, such as Merck KGaA (Germany), Thermo Fisher Scientific (United States), Celares GmbH (Germany), Astrazeneca plc (United Kingdom), Pfizer Inc. (United States), Biogen inc (United States), F. Hoffmann-La Roche Ltd (Switzerland), Horizon Pharma plc (Ireland), Shire plc (United States) and Quiapeg Pharmaceuticals Holding Ab (Sweden) etc have either set up their manufacturing facilities or are planning to start new provision in the dominated region in the upcoming years.
In August 2021, JenKem Technology provides large scale GMP manufacture of PEG derivatives for Lipid Nanoparticles (LNPs), and related PEG intermediates., In July 2021, JenKem Technology offers kilogram scale manufacture (5Kg per batch and more) of PEG and Monodisperse PEG Azide Derivatives with high purity (95%), in both GMP and non-GMP grade. and August 2020- Cadila Healthcare Limited initiated the phase II, multicenter, open-label, randomized, comparator-controlled study to evaluate the efficacy and safety of PEGylated Interferon -α2b in the treatment of adult patients diagnosed with SARS-CoV2 (COVID-19).
Market Drivers
- High Prevalence of Chronic Diseases
- Advantages offered by PEGylation
Market Trend
- Growth in Adoption of PEGylated Protein Therapeutics
Restraints
- Drug Failures and Drug Recall
- High Costs Associated with Drug Development
Opportunities
Rise in Research and Development Funding by Key Players
Challenges
Current Lack of Awareness and Stringent Regulatory Factors
AMA Research follow a focused and realistic research framework that provides the ability to study the crucial market dynamics in several regions across the world. Moreover, an in-depth assessment is mostly conducted by our analysts on geographical regions to provide clients and businesses the opportunity to dominate in niche markets and expand in emerging markets across the globe. This market research study also showcase the spontaneously changing Players landscape impacting the growth of the market. Furthermore, our market researchers extensively analyse the products and services offered by multiple players competing to increase their market share and presence.
Customization in the Report
AMA Research features not only specific market forecasts, but also include significant value-added commentary on:
- Market Trends
- Technological Trends and Innovations
- Market Maturity Indicators
- Growth Drivers and Constraints
- New Entrants into the Market & Entry/Exit Barriers
- To Seize Powerful Market Opportunities
- Identify Key Business Segments, Market Proposition & Gap Analysis
Against this Challenging Backdrop, Pegylated Proteins Study Sheds Light on
The Pegylated Proteins Market status quo and key characteristics. To end this, Analyst at AMA organize and took survey of the Pegylated Proteins industry Players. The resultant snapshot serves as a basis for understanding why and how the industry can be expected to change.
Where Pegylated Proteins industry is heading and what are the top priorities. Insights are drawn from financial analysis, the survey and interviews with key executives and industry experts.
How every company in this diverse set of Players can best navigate the emerging competition landscape and follow a strategy that helps them position to hold value they currently claim, or capture the new addressable opportunity.