Mitogen Activated Protein Kinase 8 Market Scope
MAPK8 (Mitogen-Activated Protein Kinase 8) is a Protein Coding gene. Diseases like Fatty Liver Disease and Hepatitis C are associated with MAPK8. Serine/threonine-protein kinase is involved in various processes such as cell proliferation, differentiation, migration, transformation, and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. The MAP kinases act as an integration point for multiple biochemical signals involved with a variety of cellular processes, the activation of this kinase by tumor necrosis factor-alpha if required for TNF-alpha induced apoptosis.
Bristol Myers Squibb Company (Celgene Corp) (United States), Eisai Co., Ltd. (Japan), OPKO Health (United States), Xigen SA (Switzerland) and Fulcrum Therapeutics (United States) are some of the key players that are part of study coverage.
Segmentation Overview
The study have segmented the market of Global Mitogen Activated Protein Kinase 8 market by Type (CC-90001, SR-3306, ER-358063, WBZ-4 and Others), by Application (Breast Cancer, Alzheimer's Disease, Acute Renal Failure, Liver Failure and Others) and Region with country level break-up.
On the basis of geography, the market of Mitogen Activated Protein Kinase 8 has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico).
Mitogen Activated Protein Kinase 8 Market Dynamics:
Attributes | Details |
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Growth Drivers | - Rising Demand due to Growing Prevalences of the Cancer and Gene Study
- Increasing Investment in Healthcare Sector
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Influencing Trends | - Increasing Number Cases Related to The Breast Cancer
- High Adoption of CC-90001
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Restraints | - Regulatory Concerns with Mitogen-Activated Protein Kinase 8
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Road Blocks / Challenges | - Technical Problems in Maintenance and Handling of Mitogen-Activated Protein Kinase 8
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Gaps & Opportunities | - High Demand From the Developing Countries
- Growing Demand due to Ongoing Research and Development activities across the World
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On 29 January 2020, Fulcrum Therapeutics, Inc. a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases, announced that the United States Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to losmapimod, a selective p38α/β mitogen-activated protein kinase (MAPK) inhibitor for the treatment of facioscapulohumeral muscular dystrophy (FSHD). Fulcrum also announced the issuance of U.S. patent 10,537,560 with claims covering the use of other p38 kinase inhibitors for the treatment of FSHD.
Key Target Audience
Research and Development Institutes, Potential Investors, Regulatory Bodies, Hospitals, National Laboratories and Others
About Approach
The research aims to propose a patent-based approach in searching for potential technology partners as a supporting tool for enabling open innovation. The study also proposes a systematic searching process of technology partners as a
preliminary step to select the emerging and key players that are involved in implementing market estimations. While patent analysis is employed to overcome the aforementioned data- and process-related limitations, as expenses occurred in that technology allows us to estimate the market size by evolving segments as target market from the total available market.