What is Bone Substitutes Market?
A bone substitute can be defined as a synthetic, inorganic or biologically organic combination that can be inserted for the treatment of a bone defect. These are used to provide structural support and enhance bone healing. The ideal bone substitute should be biocompatible and not evoke any adverse inflammatory response. It should be easily molded into the bone defect with a short setting time. The available bone substitutes vary in terms of mechanical properties and the rate at which they are re-absorbed. An increase in cases of bone defects across the world is driving the demand for bone substitutes. Today, bone substitutes are most widely used during spinal fusion.
The market study is being classified by Type (Bone Grafts {Autograft, Allograft, Xenograft}, Ceramics {Hydroxyapatite, Tricalcium Phosphate (TCP), Calcium Sulphate} and Growth Factors {Demineralized Bone Matrix (DBM), Platelet Rich Plasma (PRP), Bone Morphogenetic Proteins (BMPs)}), by Application (Oncologic Surgery, Traumatology, Revision Prosthetic Surgery, Spine Surgery, Dental Implants and Others) and major geographies with country level break-up.
Straumann Holding (Switzerland), Medtronic (Ireland), Stryker Corporation (United States), Johnson & Johnson (United States), Integra Lifesciences (United States), Wright Medical (United States), Zimmer Biomet (United States), Xtant Medical Holdings (United States), Arthrex (United States) and Baxter International (United States) are some of the key players profiled in the study. Additionally, the Players which are also part of the research are NovaBone Products LLC (United States), RTI Biologics (United States), Orthofix Medical (United States), Antibe Therapeutics (Canada) and Heraeus Medical GmbH (Germany).
Research Analyst at AMA predicts that United States Players will contribute to the maximum growth of Global Bone Substitutes market throughout the predicted period.
Segment Analysis
Analyst at AMA have segmented the market study of Global Bone Substitutes market by Type, Application and Region.
On the basis of geography, the market of Bone Substitutes has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico). Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth.
Market Drivers
- High Volume of Spinal Surgeries
- Rise in Adoption of Technologically Advanced Solutions by Surgeons
Market Trend
- Rising Environmental Concerns Is Increasing Demand for Organic Bone Substitutes
Restraints
Opportunities
- Rapidly Increasing Geriatric Population
- Improvements in Healthcare Infrastructure in Developing Nations
Challenges
- Developing Mechanically Strong Porous Scaffolds That Retain Proper Vascularization and Host Integration Properties
Developments are focused on improvements in the material composition and vehicles for the delivery of BMPs. These developments are likely to involve increased use of stem cells. This will reduce pressure on synthetic materials that have a negative impact on the environment.
The Food & Drug Administration of the United States (FDA) has imposed regulations on the usage of growth factors. FDA approvals include the use of PMA approved rhBMP-2 (INFUSE® Bone Graft) as an autograft replacement in spinal fusion and treatment of open tibia fractures. rhBMP-7 (OP-1® Implant) is Humanitarian Use Device (HDE) approved as an alternative to autograft in recalcitrant long bone nonunions where the use of autograft is unfeasible and alternative treatments have failed. rhBMP-7 (OP-1® Putty) is HDE approved as an alternative to autograft in compromised patients requiring revision posterolateral (intertransverse) lumbar spinal fusion, for whom autologous bone and bone marrow harvest are not feasible or are not expected to promote fusion.
Key Target Audience
Bone Substitutes Manufacturer, Bone Substitutes Healthcare Industry, Bone Substitutes Regulatory & Government Bodies, Bone Substitutes Raw Material Supplier, Bone Substitutes End-User, Bone Substitutes Government Funding Agencies and Others