Industry Background:
The CD40 ligand or CD40 pathway is widely recognized for its prominent role in immune regulation and homeostasis. CD40 is a surface antigen expressed on B cells and the CD40 ligand (CD40L) is expressed on activated T cells. Interaction between CD40 and CD40L is difficult for proliferation and isotype switching in the context of a response to a T-celldependent antigen. Patients with X-linked hyper-IgM syndrome (HIGMX-1) in their CD40L gene are unable to switch from IgM to IgG, IgE and IgA. Mice with a disrupted CD40 gene fail to undergo isotype switching to T-cell-dependent antigens but respond generally to T-independent antigens.This growth is primarily driven by Rising Prevalence of Cancer Worldwide
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Attributes | Details |
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Study Period | 2017-2027 |
Base Year | 2021 |
Forecast Period | 2022-2027 |
Historical Period | 2017-2021 |
Unit | Value (USD Million) |
Key Companies in Study | Biogen, Inc. (United States), Bristol-Myers Squibb Company (United States), eTheRNA Immunotherapies NV (Belgium), ImmuNext, Inc. (United States), Juno Therapeutics Inc. (United States), MedImmune, LLC (United States), Targovax AS (Norway), XL-protein GmbH (Germany) and FUJIFILM Irvine Scientific (United States) |
Customization Scope | Avail customization with purchase of this report. Add or modify country, region & or narrow down segments in the final scope subject to feasibility |
Globally, a noticeable market trend is evident Rising Usage of CD40 in Cancer Treatment. Major Players, such as Biogen, Inc. (United States), Bristol-Myers Squibb Company (United States), eTheRNA Immunotherapies NV (Belgium), ImmuNext, Inc. (United States), Juno Therapeutics Inc. (United States), MedImmune, LLC (United States), Targovax AS (Norway), XL-protein GmbH (Germany) and FUJIFILM Irvine Scientific (United States) etc have either set up their manufacturing facilities or are planning to start new provision in the dominated region in the upcoming years.
Key Developments in the Market:
In 2020, Novus Therapeutics, Inc. announced the acquisition of a privately-held clinical-stage biotechnology company, Anelixis Therapeutics. Anelixis develops next-generation anti-CD40 Ligand (CD40L) antibody used for treatment of organ and cellular transplantation, autoimmune diseases, and neurodegenerative diseases. The acquisition will allow Novus to develop and commercialize the next generation anti-CD40L antibody for broad range of therapeutic applications.
In 2021, CareDx and Eledon Pharmaceuticals announced the research collaboration for the discovery, development, and commercialization of AT-1501, an anti-CD40L antibody with a high affinity for CD40 Ligand. The collaboration gives Eledon access to CareDx's best-in-class technologies and develop advanced AT-1501.
Market Drivers
- Rising Prevalence of Cancer Worldwide
- Government Initiative to Improve Healthcare Services
Market Trend
- Rising Usage of CD40 in Cancer Treatment
Restraints
- Government Regulations for Protein Therapeutics
Opportunities
Rising Research Activities on CD40 Ligand
Challenges
Lack of Awareness about the Therapeutic Drug Treatment
AMA Research follow a focused and realistic research framework that provides the ability to study the crucial market dynamics in several regions across the world. Moreover, an in-depth assessment is mostly conducted by our analysts on geographical regions to provide clients and businesses the opportunity to dominate in niche markets and expand in emerging markets across the globe. This market research study also showcase the spontaneously changing Players landscape impacting the growth of the market. Furthermore, our market researchers extensively analyse the products and services offered by multiple players competing to increase their market share and presence.
Customization in the Report
AMA Research features not only specific market forecasts, but also include significant value-added commentary on:
- Market Trends
- Technological Trends and Innovations
- Market Maturity Indicators
- Growth Drivers and Constraints
- New Entrants into the Market & Entry/Exit Barriers
- To Seize Powerful Market Opportunities
- Identify Key Business Segments, Market Proposition & Gap Analysis
Against this Challenging Backdrop, CD40 Ligand Study Sheds Light on
The CD40 Ligand Market status quo and key characteristics. To end this, Analyst at AMA organize and took survey of the CD40 Ligand industry Players. The resultant snapshot serves as a basis for understanding why and how the industry can be expected to change.
Where CD40 Ligand industry is heading and what are the top priorities. Insights are drawn from financial analysis, the survey and interviews with key executives and industry experts.
How every company in this diverse set of Players can best navigate the emerging competition landscape and follow a strategy that helps them position to hold value they currently claim, or capture the new addressable opportunity.