Alagille Syndrome Market Scope
Alagille syndrome is a rare genetic disease that mainly affects the liver. The after-effect then spreads to other organs of the body. In Alagille syndrome, bile builds up because the liver has fewer small bile ducts. An uncommon hereditary condition known as Alagille syndrome primarily affects the liver. The consequences subsequently spread to the body's other organs. One of the key factors driving the market's expansion is the rising incidence of cancer on a global scale. Other factors supporting the market's development include increasing spending on the construction of healthcare infrastructure and a rise in demand for novel cures and treatments. Other indirect factors that will generate profitable market growth prospects include increased paraganglioma incidences, increasing personal disposable income, and strategic collaboration and licensing agreements among the leading companies to develop treatments. However, the lack of knowledge caused by the rarity of the diseases and the unfavorable reimbursement situation in developing and underdeveloped nations would be a significant obstacle to the market's expansion. An increasing number of recalls would further hamper the market growth rate. This in turn can cause liver scarring and damage. Increasing prevalence of cancer across the world is a major factor driving the growth of the market. Also, increasing expenditure on healthcare infrastructure development and growing demand for new medical and nursing care are also contributing factors to the growth of the market. Strategic collaboration and licensing agreements between key players in the development of therapeutic drugs, growing paragangliomas and personal disposable income are some other indirect factors creating lucrative opportunities for market growth.
Attributes | Details |
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Study Period | 2020-2032 |
Base Year | 2024 |
Unit | Value (USD Million) |
Key Companies Profiled | Albireo Pharma, Inc. (United States), Bioarray S.L. (Spain), Mirum Pharmaceuticals (United States), Zydus Cadila (India), ALLERGAN (Ireland), Teva Pharmaceutical Industries Ltd. (Israel), Takeda Pharmaceutical Company Limited (Japan), AstraZeneca (United Kingdom), Lupin Pharmaceuticals, Inc. (India), GlaxoSmithKline plc (United Kingdom) and Endo International plc (Ireland) |
CAGR | % |
The companies are exploring the market by adopting mergers & acquisitions, expansions, investments, new service launches and collaborations as their preferred strategies. The players are exploring new geographies through expansions and acquisitions to avail a competitive advantage through combined synergies. Research Analyst at AMA estimates that Global Players will contribute to the maximum growth of Global Alagille Syndrome market throughout the predicted period.
Albireo Pharma, Inc. (United States), Bioarray S.L. (Spain), Mirum Pharmaceuticals (United States), Zydus Cadila (India), ALLERGAN (Ireland), Teva Pharmaceutical Industries Ltd. (Israel), Takeda Pharmaceutical Company Limited (Japan), AstraZeneca (United Kingdom), Lupin Pharmaceuticals, Inc. (India), GlaxoSmithKline plc (United Kingdom) and Endo International plc (Ireland) are some of the key players that are part of study coverage. Additionally, the Players which are also part of the research are Pfizer Inc. (United States),, Novartis AG (Switzerland), Glenmark Pharmaceuticals Ltd. (India), Amneal Pharmaceuticals LLC (United States) and Bristol-Myers Squibb Company (United States).
About Approach
The research aims to propose a patent-based approach in searching for potential technology partners as a supporting tool for enabling open innovation. The study also proposes a systematic searching process of technology partners as a preliminary step to select the emerging and key players that are involved in implementing market estimations. While patent analysis is employed to overcome the aforementioned data- and process-related limitations, as expenses occurred in that technology allows us to estimate the market size by evolving segments as target market from the total available market.
Segmentation Overview
The study have segmented the market of Global Alagille Syndrome market by Type and Region with country level break-up.
On the basis of geography, the market of Alagille Syndrome has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico).
region held largest market share in the year 2024.
Market Leaders and their expansionary development strategies
In June 2024, Takeda Pharmaceutical Company submitted a new drug application in Japan for maralixibat to treat ALGS and progressive familial intrahepatic cholestasis (PFIC).
In September 2024, Ipsen received approval from the European Commission for Kayfanda (odevixibat) to treat cholestatic pruritus in patients aged six months and older with ALGS.
Influencing Trend:
Advancements in genetic testing
Market Growth Drivers:
Increasing number of healthcare and pharmaceutical facilities globally and Rising research and development opportunities for alagille syndrome
Challenges:
Lack of specific treatment options
Restraints:
High development costs and regulatory challenges
Opportunities:
Focus on Developing New Drugs and Technological advancement in the development of new therapeutic treatment
Key Target Audience
Venture Capitalists and Private Equity Firms, New Entrants/Investors, Strategic Business Planners, Government Regulatory, Research Organizations, End-Use Industries and Others