About Isothermal amplification
In order to study individual genes or specific DNA regions of interest, it's often necessary to obtain a large amount of nucleic acid for study. Rather than isolate one copy of the target DNA from a large number of cells, it's often additional help to get multiple copies of a target from one molecule of DNA or mRNA, via an in vitro amplification method. Isothermal amplification methods provide detection of a nucleic acid target sequence in a very efficient, exponential manner, and don't seem to be restricted by the constraint of thermal cycling. Although these methods will vary significantly, they all share some options in common. For example, because the polymer strands are not heat-denatured, all equal strategies deem an alternate approach to modify primer binding and initiation of the amplification reaction: a polymerase with strand-displacement activity. Once the reaction is initiated, the polymerase should also separate the strand that's still annealed to the sequence of interest. Isothermal amplification chemistry has been applied to diagnostics with polymerase success and is employed in many industrial molecular diagnostic platforms, serving large testing centers and point-of-care markets. Equal Amplification is turning into additional and additional standards as an easy and cost-effective alternative to standard PCR.
Attributes | Details |
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Study Period | 2018-2030 |
Base Year | 2023 |
Unit | Value (USD Million) |
The companies are exploring the market by adopting mergers & acquisitions, expansions, investments, new service launches, and collaborations as their preferred strategies. The players are exploring new geographies through expansions and acquisitions to avail a competitive advantage through combined synergies. Analyst at AMA Research estimates that United States Players will contribute the maximum growth to Global Isothermal amplification market throughout the forecasted period. Established and emerging Players should take a closer view at their existing organizations and reinvent traditional business and operating models to adapt to the future.
Becton, Dickinson & Company (United States), Hologic, Inc. (United States), Grifols, S.A. (Spain), EIKEN CHEMICAL CO., LTD. (Japan), Meridian Bioscience (United States), Quidel Corporation (United States), QIAGEN (Netherlands), bioMérieux SA (France), Tecan Trading AG (Switzerland), DiaSorin S.p.A. (Italy), Abbott Laboratories, Inc. (United States), Thermo Fisher Scientific, Inc. (United States), GE Healthcare (United States), Illumina, Inc. (United States), New England Biolabs, Inc. (United States), TwistDx Limited (United States), Mast Group Ltd. (United Kingdom), Lucigen Corporation (United States) and Ustar Biotechnologies Ltd. (China) are some of the key players that are part of study coverage. Additionally, the Players which are also part of the research coverage are Genomtec SA (Poland), Jena Bioscience GmbH (Germany), OptiGene Limited (United Kingdom), Sysmex Corporation (Japan), PREMIER Biosoft (United States) and mFluiDx (United States).
Segmentation Overview
AMA Research has segmented the market of Global Isothermal amplification market by Type (Instruments and Reagents), Application (Blood Screening, Infectious Disease Diagnosis and Other) and Region.
On the basis of geography, the market of Isothermal amplification has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico). If we see Market by Technology, the sub-segment i.e. TMA will boost the Isothermal amplification market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by End User, the sub-segment i.e. Hospitals will boost the Isothermal amplification market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth.
Influencing Trend:
Rising Adoption of The Isothermal Amplification
Market Growth Drivers:
Increase in Viral Diseases, Growing in Prevalence of Cancer, Rise in Demand for Low-cost and Effective Diagnostics Procedures and A Rise in The Miniaturization of Nucleic Acid-based Diagnostics
Challenges:
Lack of Skilled Professional and Lack of Awareness about New Diagnostics Technologies
Restraints:
High Cost of The Methods and Threatening Opposition from PCR Technologies
Opportunities:
Increasing Technological Advancements
Market Leaders and their expansionary development strategies
In 2018, Tecan, a laboratory instruments and solutions provider had acquired Nugen Technologies. The acquisition had helped Tecan for expanding into a new market segment of next-generation sequencing (NGS) reagents.
In November 2021, Meridian Bioscience, Inc, a leading global provider of diagnostic testing solutions and life science raw materials, announced the launch of its Air-Dryable LAMP Mix and Air-Dryable RT-LAMP 1-Step Mix. These ground-breaking molecular master mixes are specifically designed for fast isothermal amplification of nucleic acid sequences, not only to facilitate the development of point-of-care ambient temperature-stable assays, but also to accelerate diagnosis.
Key Target Audience
New Entrants/Investors, Analysts and Strategic Business Planners, Providers of Isothermal amplification, Venture Capitalists and Private Equity Firms and End-Use Industry
About Approach
To evaluate and validate the market size various sources including primary and secondary analysis is utilized. AMA Research follows regulatory standards such as NAICS/SIC/ICB/TRCB, to have a better understanding of the market. The market study is conducted on basis of more than 200 companies dealing in the market regional as well as global areas with the purpose to understand the companies positioning regarding the market value, volume, and their market share for regional as well as global.
Further to bring relevance specific to any niche market we set and apply a number of criteria like Geographic Footprints, Regional Segments of Revenue, Operational Centres, etc. The next step is to finalize a team (In-House + Data Agencies) who then starts collecting C & D level executives and profiles, Industry experts, Opinion leaders, etc., and work towards appointment generation.
The primary research is performed by taking the interviews of executives of various companies dealing in the market as well as using the survey reports, research institute, and latest research reports. Meanwhile, the analyst team keeps preparing a set of questionnaires, and after getting the appointee list; the target audience is then tapped and segregated with various mediums and channels that are feasible for making connections that including email communication, telephonic, skype, LinkedIn Group & InMail, Community Forums, Community Forums, open Survey, SurveyMonkey, etc.