About Sezary Syndrome
Sezary syndrome is an extreme form of cutaneous T-cell lymphoma, a category of diseases that arise as T-cells (a lymphocyte) become cancerous and spread to the skin, number of Mycosis fungoides (MF) patients appear with only patches and plaques, and the lesions are generally skin-based. Sezary syndrome can affect people of any age, but it is more frequent in adults aged 50 and over, and men are marginally more likely than women to develop it. Sezary cells, cancerous T cells present in the skin, lymph nodes, and blood, are termed Sezary cells in Sezary syndrome (SS). Patients with relapsed or refractory SS/MF have a low prognosis, and alternative therapy approaches have high relapse rates, so there is an unmet need for an effective treatment.
Attributes | Details |
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Study Period | 2019-2029 |
Base Year | 2023 |
Unit | Value (USD Million) |
The companies are exploring the market by adopting mergers & acquisitions, expansions, investments, new service launches and collaborations as their preferred strategies. The players are exploring new geographies through expansions and acquisitions to avail a competitive advantage through combined synergies. Analyst at AMA Research estimates that United States & Japanese Players will contribute the maximum growth to Global Sezary Syndrome market throughout the forecasted period. Established and emerging Players should take a closer view at their existing organizations and reinvent traditional business and operating models to adapt to the future.
Merck & Co. Inc. (Germany), Bayer AG (Germany), Novartis AG (Switzerland), Shionogi Inc. (Japan), Kyowa Hakko Kirin Co. Ltd. (Japan), Innate Pharma SA (France), Bioniz (United States), Minophagen Pharmaceutical Co. Ltd (Japan), Gilead Sciences Inc. (United States) and Seattle Genetics Inc. (United States) are some of the key players that are part of study coverage. Additionally, the Players which are also part of the research coverage are Hikma Pharmaceuticals PLC (United Kingdom), STI Pharma LLC (United States), Eisai Co. Ltd (Japan) and Amerigen Pharmaceuticals Limited (United States).
Segmentation Overview
AMA Research has segmented the market of Global Sezary Syndrome market by , Application (Hospitals and Specialty Clinics) and Region.
On the basis of geography, the market of Sezary Syndrome has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico). If we see Market by Drug, the sub-segment i.e. Vorinostat will boost the Sezary Syndrome market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by Treatment, the sub-segment i.e. Standard Treatment (Photodynamic Therapy, Radiation Therapy, Chemotherapy) will boost the Sezary Syndrome market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by Diagnosis, the sub-segment i.e. Immunophenotyping will boost the Sezary Syndrome market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth.
Influencing Trend:
Increasing R&D on in Healthcare industry
Market Growth Drivers:
Rising Healthcare Awareness and Growth in Healthcare and Pharma Infrastructure
Challenges:
Regional Regulatory Approval and Fierce Competitive Pressure
Restraints:
Lack of Trained Professionals and Side Effects and Adverse Drug Reactions
Opportunities:
Low Penetration in Asian Region
Market Leaders and their expansionary development strategies
Dec 2022: Citius Pharmaceuticals Inc. announced that the US FDA accepted the company's biologics license application (BLA) for denileukin diftitox, an engineered IL-2-diphtheria toxin fusion protein for the treatment of patients with persistent or recurrent CTCL.
On 21st December, 2020 – Researchers at H. Lee Moffitt Cancer Center & Research Institute Discovered New Drug Target to Treat Cutaneous T Cell Lymphoma, This New Drug Blocks Methylation, Restores SATB1 Expression and Is Claimed to Be Effective Against the Syndrome. and On 13th January, 2020 – Innate Pharma SA Received Regulatory Clearance from the French Regulatory Authority to Resume the Phase II of the Clinical Trials of Innate’s lacutamab (IPH4102) for the Treatment of Sezary Syndrome and Mycosis Fungoides (MF).
United States, Food and Drug Administration “Non-Hodgkin lymphoma Drugs Approval” - USDA is the key Regulatory Authority Responsible for Approval, Inspection and Dosage Limitations of Therapeutic Drugs across the United States, FDA limits the usage to licensed prescription holders only. Any New Entrant is Required to have a Regulatory Clearance form FDA.
Key Target Audience
The companies are exploring the market by adopting mergers & acquisitions, expansions, investments, new service launches and collaborations as their preferred strategies. The players are exploring new geographies through expansions and acquisitions to avail a competitive advantage through combined synergies.
About Approach
To evaluate and validate the market size various sources including primary and secondary analysis is utilized. AMA Research follows regulatory standards such as NAICS/SIC/ICB/TRCB, to have a better understanding of the market. The market study is conducted on basis of more than 200 companies dealing in the market regional as well as global areas with the purpose to understand the companies positioning regarding the market value, volume, and their market share for regional as well as global.
Further to bring relevance specific to any niche market we set and apply a number of criteria like Geographic Footprints, Regional Segments of Revenue, Operational Centres, etc. The next step is to finalize a team (In-House + Data Agencies) who then starts collecting C & D level executives and profiles, Industry experts, Opinion leaders, etc., and work towards appointment generation.
The primary research is performed by taking the interviews of executives of various companies dealing in the market as well as using the survey reports, research institute, and latest research reports. Meanwhile, the analyst team keeps preparing a set of questionnaires, and after getting the appointee list; the target audience is then tapped and segregated with various mediums and channels that are feasible for making connections that including email communication, telephonic, skype, LinkedIn Group & InMail, Community Forums, Community Forums, open Survey, SurveyMonkey, etc.