About Dysautonomia
Dysautonomia is a disorder of autonomic nervous system (ANS) function which generally involves the failure of sympathetic components of the ANS, it also involves excessive or overactive ANS. It occurs as a primary condition or with degenerative neurological diseases like Parkinson's disease various other generalized primary dysautonomia includes multiple system atrophy and family history dysautonomia. Several common conditions such as diabetes and alcoholism can include also include dysautonomia. Right now there is no cure for dysautonomia, its secondary forms might improve with the therapy of an underlying disease. Methods to treat or combat with hypotension include elevation of the head of the bed, water bolus, high salt diet and drugs such as fludrocortisone and midodrine.
Attributes | Details |
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Study Period | 2018-2028 |
Base Year | 2022 |
Unit | Value (USD Million) |
Individuals living with dysautonomia face a complex landscape of medical professionals, research institutions, and support groups. It's crucial to build a strong team of healthcare providers who understand dysautonomia and can work together to develop a personalized treatment plan. Joining patient support groups and online communities can also provide valuable information, connection, and emotional support. Established and emerging Players should take a closer view at their existing organizations and reinvent traditional business and operating models to adapt to the future.
Novartis Pharmaceuticals Corporation (Switzerland), Corlanor (Amgen Inc.) (United States), NORTHERA (Lundbeck NA Ltd.) (United States), Teva Cares Foundation (Teva Pharmaceutical Industries, Ltd) (United States), Pfizer Inc. (United States), Celltex Therapeutics Corporation (United States), Merck Sharp & Dohme Corp. (United States), Theravance Biopharma (United States), Shire Development, Inc. (United States) and H. Lundbeck A/S (Denmark) are some of the key players that are part of study coverage. Additionally, the Players which are also part of the research coverage are Axsome Therapeutics, Inc. (United States), Medtronic (Dublin, Ireland), Biotronik (Germany), Nfocus Neuro (United States) and Cala Health (United States).
Segmentation Overview
AMA Research has segmented the market of Global Dysautonomia market by Type (Neurocardiogenic Syncope, Postural Orthostatic Tachycardia Syndrome, Multiple System Atrophy, Autonomic Dysreflexia, Baroreflex Failure and Others) and Region.
On the basis of geography, the market of Dysautonomia has been segmented into South America (Brazil, Argentina, Rest of South America), Asia Pacific (China, Japan, India, South Korea, Taiwan, Australia, Rest of Asia-Pacific), Europe (Germany, France, Italy, United Kingdom, Netherlands, Rest of Europe), MEA (Middle East, Africa), North America (United States, Canada, Mexico). If we see Market by Treatment, the sub-segment i.e. Physical Therapy will boost the Dysautonomia market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth. If we see Market by Tests, the sub-segment i.e. Cardiovagal and Vasomotor Function Tests will boost the Dysautonomia market. Additionally, the rising demand from SMEs and various industry verticals gives enough cushion to market growth.
Influencing Trend:
Increasing Exercises and Counseling Related Treatment for Dysautonomia and Prevalence of Neurocardiogenic Syncope and Postural Orthostatic Tachycardia Syndrome forms of Dysautonomia
Market Growth Drivers:
Increasing Prevalence of Diabetic and Degenerative Neurological Diseases and Rising Number of Problems with Peripheral Nerves
Challenges:
Stiff Competition Among Players
Restraints:
Regulatory Compliance Regarding Dysautonomia and Expensive Dysautonomia Treatment Therapies
Opportunities:
Continuous Research and Development in the Drugs and Treatment for Dysautonomia
Market Leaders and their expansionary development strategies
In October 2023, BioXcel Therapeutics and Dysautonomia International partner to develop a novel dysautonomia treatment this collaboration focuses on bringing BioXcel's drug candidate, BXCL501, through clinical trials for the treatment of postural orthostatic hypotension (POTS), a common symptom of dysautonomia.
In September 2023, NIH funds research on wearable sensor and AI system for postural tachycardia syndrome (POTS) this project aims to develop a system that continuously monitors vital signs and uses AI to predict and prevent POTS symptoms, a common form of dysautonomia.
"Numerous automated ANS testing devices have been cleared for marketing by the U.S. Food and Drug Administration through the 510k process (e.g., QHRV System, VitalScan, ANSAR ANX, ZYTO Scan Hand Cradle, Neuropad, Sudoscan, EZScan, Natus VikingQuest, Bodytronic 200). These devices, along with newer methodologies (e.g., quantitative direct and indirect testing of sudomotor function [QDIRT]) propose to generate data after approximately 10-15 minutes of testing and without physician interpretation. According to the American Academy of Neurology, these methods and/or devices have insufficient published literature to establish clinical utility. Many devices are severely limited in the validity of the data they generate because they do not measure or control for expiratory pressure or include beat-to-beat blood pressure measurement, both of which are requirements, not only for scientifically accurate assessment but also for billing of autonomic testing."
Key Target Audience
Dysautonomia Testing Devices Manufacturers, Dysautonomia Treatment Association and Institutes, Regulatory Bodies, Dysautonomia Drugs and Testing Equipment Investors and Others
About Approach
To evaluate and validate the market size various sources including primary and secondary analysis is utilized. AMA Research follows regulatory standards such as NAICS/SIC/ICB/TRCB, to have a better understanding of the market. The market study is conducted on basis of more than 200 companies dealing in the market regional as well as global areas with the purpose to understand the companies positioning regarding the market value, volume, and their market share for regional as well as global.
Further to bring relevance specific to any niche market we set and apply a number of criteria like Geographic Footprints, Regional Segments of Revenue, Operational Centres, etc. The next step is to finalize a team (In-House + Data Agencies) who then starts collecting C & D level executives and profiles, Industry experts, Opinion leaders, etc., and work towards appointment generation.
The primary research is performed by taking the interviews of executives of various companies dealing in the market as well as using the survey reports, research institute, and latest research reports. Meanwhile, the analyst team keeps preparing a set of questionnaires, and after getting the appointee list; the target audience is then tapped and segregated with various mediums and channels that are feasible for making connections that including email communication, telephonic, skype, LinkedIn Group & InMail, Community Forums, Community Forums, open Survey, SurveyMonkey, etc.